Skip to content

KissPeptin-10

♢ Research use only Especificação ao nível da classe; lotes selecionados testados pela Janoshik

✓ Janoshik Verified 99.849%KissPeptin-10 · Report #233649 ↗
TAMANHO

Free standard EU shipping on orders over €200

If a product doesn't match the specification on its published COA, contact us with your batch number: we investigate against the lot's report and replace any product that fails it, at no cost to you.

Contact us within 48 hours of delivery with photos of the outer box, inner packing, and any affected vials with labels legible. Confirmed transit damage is replaced at no cost to you.

Returns policy →
Shipping estimate for EU

3–7 days most of the EU · 10–14 Nordics/Baltics. Dispatched within 1–2 business days. Check destination rates at checkout.

Full shipping information

KissPeptin-10 de grau de investigação. Especificação ao nível da classe ≥98%; lotes selecionados testados independentemente. Pó liofilizado em frasco de vidro selado. Apenas para fins de investigação. Não destinado ao consumo humano.

Descrição

Kisspeptin-10 is the minimum active fragment of the kisspeptin family — a 10-amino acid C-terminal peptide derived from the KISS1 gene product. It binds the kisspeptin receptor (GPR54/KISS1R) and is the most potent naturally occurring kisspeptin isoform at this receptor. Kisspeptins are the most important upstream activators of GnRH neurons, making them the master regulators of reproductive function and central integrators of metabolic state with fertility.

The discovery of kisspeptin’s role in GnRH regulation in 2003-2004 was a significant advance in reproductive endocrinology. Prior to this, the signal that drove GnRH neurons was not clearly identified. Kisspeptin neurons in the arcuate nucleus and the anteroventral periventricular nucleus receive metabolic and hormonal inputs — leptin, sex steroids, thyroid hormones, metabolic state — and translate these into GnRH drive. This makes kisspeptin the integration point between metabolic and reproductive signalling studied in models: how energy balance is coupled to GnRH drive, and how puberty timing relates to body weight in research models.

Research applications include stimulation testing of the HPG axis (kisspeptin-10 stimulation paradigm to assess GnRH neuron function), study of GnRH-axis signalling in hypothalamic hypogonadism models, and research into the neuroendocrine control of puberty and reproduction.

Specifications

Parameter Value
Compound Kisspeptin-10 (KISS1 decapeptide, C-terminal fragment)
Pureza ≥98% (class-level specification)
Format Lyophilized powder
Reconstitution Sterile water or saline
Conservação -20°C; 2-8°C after reconstitution

Conservação

Store at -20°C before reconstitution. Refrigerate at 2-8°C after reconstitution and use within 14 days. Protect from repeated freeze-thaw cycles.

How does kisspeptin control GnRH release?

Kisspeptin neurons in the hypothalamus (particularly in the arcuate nucleus for pulsatile GnRH regulation, and the anteroventral periventricular nucleus for the preovulatory LH surge) project directly to GnRH neurons, which express KISS1R. In research models, when kisspeptin binds KISS1R on GnRH neurons it is studied for its role in potently stimulating GnRH release. The arcuate kisspeptin neurons, which also co-express neurokinin B and dynorphin (KNDy neurons), are studied as the GnRH pulse generator — the coordinated activity associated with pulsatile GnRH secretion that underlies LH and FSH secretion in model systems.

Why is kisspeptin important for understanding metabolic-reproductive connections?

Kisspeptin neurons receive input from leptin receptors, and leptin (the adipocyte hormone that signals nutritional adequacy) is required for normal kisspeptin neuron activity. In leptin-deficient or leptin-resistant states modelled in research, kisspeptin signaling is impaired and GnRH drive is reduced. This is studied to understand why severe nutritional restriction and extreme exercise suppress reproductive signalling in models — the body uses kisspeptin as a gate through which metabolic status must pass before reproductive function proceeds. Kisspeptin research is central to understanding how energy balance and reproduction are coupled.

What is the kisspeptin stimulation paradigm?

The kisspeptin stimulation paradigm administers kisspeptin-10 (or kisspeptin-54) and measures LH, FSH, and testosterone/estradiol response. Unlike the standard GnRH stimulation paradigm which probes pituitary function, the kisspeptin paradigm examines the GnRH neuron and pituitary together — it tests whether GnRH neurons can respond to kisspeptin and whether the pituitary can respond to the resulting GnRH release. This allows distinction between GnRH neuron dysfunction (no response to kisspeptin) and pituitary dysfunction (response to GnRH direct stimulation but not to kisspeptin). Research groups in the UK have published kisspeptin stimulation protocols.

Kisspeptin-10 is supplied for research purposes only. Not for human use. Handle in compliance with institutional biosafety guidelines.

ParâmetroValor
CompostoKisspeptin-10 (decapéptido KISS1, fragmento C-terminal)
Pureza≥98% (especificação ao nível da classe)
FormatoPó liofilizado
ReconstituiçãoÁgua estéril ou solução salina
Armazenamento-20°C; 2-8°C após reconstituição

KissPeptin-10

KissPeptin-10 · Result: 99.849% · Measured content: 10.94 mg (109.4% of label) · Report Code: BFDKY9EV6Z9D · Test Date: 2026-09-18 · Lab: Janoshik Analytical

View independent report #233649 ↗

Follow the storage conditions on the product label and its published documentation. Handle only in an appropriately equipped laboratory.

Peptide Reconstitution Calculator →

Confiança do investigador

Porque é que os investigadores escolhem a CertaPeptides

Quem testa isto efetivamente?

Lotes selecionados são verificados de forma independente pela Janoshik Analytical (República Checa) e publicados no portal público da Janoshik. Outros lotes são enviados com a especificação de lote do fornecedor. Consulte /coa para ver a lista publicada.

Ver COA →

E se eu receber o lote errado?

Cada rótulo de frasco contém um código. Procure-o na nossa página de verificação: esta mostra o que a CertaPeptides publica para esse código e, para um lote retirado, que o lote foi retirado e porquê. Se o seu lote tiver sido retirado, ou se a pesquisa do código do seu rótulo não devolver resultados, envie-nos esse código por e-mail.

Ver COA →

De onde é enviado?

Roménia (UE). Somos a CERTALAB SRL, CUI 54169956, registada para efeitos de IVA. Sameday para a Roménia, GLS para a maioria dos destinos da UE, TCE Worldwide para os restantes mercados transfronteiriços da UE e fora da UE (Reino Unido, Suíça). Entrega em 1–15 dias úteis, dependendo do destino — janela exata apresentada no checkout.

Detalhes de envio →

E se houver um problema?

Tem um direito de livre resolução de 14 dias ao abrigo da OUG 34/2014 (legislação romena/da UE em matéria de consumidores), com possibilidade de escalonamento para ANPC e de resolução alternativa de litígios (SAL). Contacte-nos em support@chinapeptideshop.com.

Política de devoluções →

Informações do produto

Este produto destina-se apenas a fins de investigação e desenvolvimento científico. É uma substância química que não deve ser utilizada como fármaco, medicamento, substância ativa ou ingrediente em qualquer produto destinado ao consumo humano ou animal. Os investigadores devem manusear este composto em conformidade com as diretrizes de biossegurança da sua instituição. Utilize apenas em instalações laboratoriais devidamente equipadas e com equipamento de proteção individual adequado.

Perguntas frequentes

Biblioteca de investigação

Artigos de investigação relacionados

Ver todos

Frequently researched together

Combined Price €153.96

View All Products
Recomende um investigador

Fale com outro investigador

Ofereça 15% de desconto e ganhe 10% de retorno na primeira encomenda que ele fizer.

KissPeptin-10Research use only
Added to cart

Essential cookies keep your cart and account working. Optional content is disabled until you allow it.

europa.eu/youreurope/garantias

Customer support

Live chat is not connected yet. Please contact our support team by email.

support@chinapeptideshop.com