MT-2 (Melanotan 2 Acetate)
MT-2 (Melanotan 2 Acetate) · Result: 99.455% · Measured content: 10.45 mg (104.5% of label) · Report Code: PALC8VXE3661 · Test Date: 2026-09-18 · Lab: Janoshik Analytical
View independent report #233663 ↗Melanocortin and Pigment Research Peptides SKU: CP-MT2
MT-2 (Melanotan 2 Acetate)
♢ Research use only Špecifikácia na úrovni triedy; vybrané šarže testuje Janoshik
✓ Janoshik Verified 99.455%MT-2 (Melanotan 2 Acetate) · Report #233663 ↗Free standard EU shipping on orders over €200
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Full shipping informationMelanotan II (MT-2) je syntetický cyklický heptapeptidový analóg alpha-MSH so silnou agonistickou aktivitou na melanokortínových receptoroch. Viaže sa na MC1R, MC3R, MC4R, MC5R. Skúmaný vo výskumných modeloch z hľadiska melanogenézy a energetickej homeostázy. Dodáva sa ako lyofilizovaný prášok; špecifikácia na úrovni triedy ≥98%; vybrané šarže sú nezávisle testované. Len na výskumné účely. Nie je určené na ľudskú spotrebu.
O produkte MT-2 (Melanotan 2 Acetate)
Melanotan II (MT-2) is a synthetic cyclic analogue of alpha-MSH (alpha-melanocyte-stimulating hormone), a peptide derived from POMC (proopiomelanocortin). It is a potent, non-selective agonist at melanocortin receptors (MC1R through MC5R), with particularly strong activity at MC1R and MC4R. This broad agonism is studied in research models in connection with both its well-characterised activity on skin pigmentation (via MC1R) and its research history around sexual-arousal pharmacology and appetite modulation (via MC4R).
The pharmacology is worth understanding in some detail. MC1R is expressed on melanocytes and regulates melanin production — in research models MT-2 is studied for activation of eumelanin synthesis, associated with darker skin pigmentation without UV exposure. MC4R is expressed in the hypothalamus and plays roles in melanocortin signalling and sexual function — in research models its activation is studied for satiety signalling and, notably, pro-erectile effects in male rodent models. MC3R has roles in energy homeostasis. MT-2 activates all of these nonselectively, which produces the compound’s range of effects in research models and also complicates research interpretation where receptor-specific effects need to be isolated.
MT-2 was developed at the University of Arizona from research aimed at characterizing a compound that would drive melanin synthesis in model systems and, in turn, was studied in the context of UV-related skin biology. The broader melanocortin agonism effects became apparent during development. It has been investigated in preclinical research on sexual-arousal pharmacology, and a related derivative (bremelanotide/PT-141) shares the same MC4R-mediated mechanism.
Specifications
| Parameter | Value |
|---|---|
| Compound | Melanotan II acetate (cyclic alpha-MSH analogue) |
| Čistota | ≥98% (class-level specification) |
| Format | Lyophilized powder |
| Reconstitution | Bacteriostatic water |
| Skladovanie | -20°C; 2-8°C after reconstitution, protect from light |
Skladovanie
Store at -20°C and protect from light. MT-2 is light-sensitive. Refrigerate after reconstitution at 2-8°C. Lyophilized powder is stable for 24+ months under proper storage.
What melanocortin receptors does MT-2 activate?
MT-2 is a non-selective melanocortin receptor agonist with activity at MC1R, MC3R, MC4R, and MC5R. MC1R mediates skin and hair pigmentation (studied in research models for activation of eumelanin synthesis in melanocytes). MC3R and MC4R are expressed in the hypothalamus and have roles in energy homeostasis, appetite, and sexual function. In research models, MC4R activation is studied for MT-2’s pro-erectile effects in rodent models and its satiety effects. MC5R has roles in exocrine gland function. MT-2’s lack of receptor selectivity is a key consideration for research design when receptor-specific effects need to be distinguished.
How does MT-2 relate to PT-141 (bremelanotide)?
PT-141 (bremelanotide) is a metabolite of MT-2 that differs only at the C-terminus (a free acid instead of an amide); both peptides are cyclic. In research, it is the compound associated with the MC4R-mediated sexual-arousal pharmacology rather than the tanning or other melanocortin effects. MT-2 is the research precursor that established the MC4R-mediated arousal pharmacology that PT-141 was developed from.
What was the original research goal for MT-2?
MT-2 was developed at the University of Arizona in the 1980s-90s with the goal of characterizing a compound that would produce melanin synthesis without UV exposure in model systems, studied in the context of UV-related skin biology. The pro-pigmentation activity via MC1R was the primary target. The broader melanocortin receptor agonism — including the MC4R-mediated effects on sexual arousal and appetite in animal models — was discovered during development and shifted the research direction significantly.
Melanotan II is supplied for research purposes only. Not for human use. Handle in compliance with institutional biosafety guidelines.
| Parameter | Hodnota |
|---|---|
| Zlúčenina | Melanotan II acetate (cyklický analóg alpha-MSH) |
| Čistota | ≥98% (špecifikácia na úrovni triedy) |
| Forma | Lyofilizovaný prášok |
| Rekonštitúcia | Bakteriostatická voda |
| Skladovanie | -20°C; 2-8°C po rekonštitúcii, chrániť pred svetlom |
Follow the storage conditions on the product label and its published documentation. Handle only in an appropriately equipped laboratory.
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Zásady vrátenia tovaru →Informácie o produkte
Tento produkt je určený výhradne na účely vedeckého výskumu a vývoja. Ide o chemickú látku, ktorá sa nesmie používať ako liek, liečivo, účinná látka ani zložka akéhokoľvek produktu určeného na ľudskú alebo zvieraciu konzumáciu. Výskumníci musia s touto zlúčeninou manipulovať v súlade so svojimi inštitucionálnymi zásadami biologickej bezpečnosti. Používajte len v riadne vybavených laboratórnych priestoroch s vhodnými osobnými ochrannými prostriedkami.
Peptidy v lyofilizovanej (mrazom sušenej) forme sa odosielajú v zatavených sklenených liekovkách štandardnými spôsobmi doručenia a počas prepravy nevyžadujú chladenie. Lyofilizované peptidy sú vysoko stabilné pri okolitých teplotách počas celej štandardnej prepravy (typické tranzitné okná sú uvedené v pokladni). Po prijatí produkt bezodkladne premiestnite do chladeného skladu (2 – 8 °C).
Časté otázky
Výskumné peptidy sa dodávajú v lyofilizovanej (mrazom sušenej) forme. Množstvo materiálu je zvyčajne len niekoľko miligramov — javí sa ako veľmi tenká vrstva alebo malá peletka na dne liekovky, často takmer neviditeľná. Toto je úplne normálne.
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